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Author: zerophoid


Thank you for visiting my page. This forum will be presenting medical cases in various fields such as CFS, Fibromyalgia, Rheumatoid Arthritis, Scleroderma, Lupus, Multiple Sclerosis and other neuropathies, Polymyositis, heart conditions, lung conditions, ophtalmic conditions, renal and liver conditions, and various skin diseases. The links between these conditions will be shown as a chronic or acute vasculitis.
Please feel free to share any comments you may have.

What could be an auto immune condition?

A patient came to me with three auto immune conditions:
– Crohn’s disease
– Rheumatoid arthritis
– Psoriasis

She had three specialists taking care of each condition with the same approach: cortisone, methotrexate and biological treatments.

Do we speak about three different bodies or one ravaged by similar pathogens in different organs?

Highlighting neurological and psychiatric conditions

Author: Professor JB Jadin
Provincial Institut voor Hygiene, Antwerpen, Belgium

This article was presented at the International Meeting 
‘RICKETTSIOLOGY: The present and the future’

Palermo ( Italy) 21-28 June 1987

Most nervous diseases have been described by symptoms proceeding from observations made by clinicians rather than by histo-pathological and biological studies.
In this paper we want to show how, after fifty years of research on the subject with Henri Baruk, we think we have come to a turning point on neurology, neurological etiology.
Consequently, a number of nervous diseases considered, up to now, as incurable, can be successfully treated for as much as their physical state is not too impaired.

Most nervous diseases have been described by symptoms observed clinically, rather than biological studies and histopathology.
Undoubtedly, most diseases are well known and their etiomology has been identified. Nevertheless quite a number of them, for instance the disease of Guilain Barre, syringo-myelie, disease of Creutzfeldt-Jacob, are described as viral affections, due to one of many viruses which attack man during life and are, one after another, being isolated.
Observations which we have kept on since more than fifty years, have led us to think that protozoa viruses and bacteria, if associated, may be very important in nervous diseases. 
(Jadin J.B., Giroud P., Jadin J.M., 1984)
The damage caused on the brain by trypanosoma in Central Africa is well known. But often trypanosoma is not only responsible for the bad physical conditions observed during this terrible disease. Indeed, in many regions, trypanosoma live in symbiosis with man without any effect. For instance, in Zimbabwe where Blair (1939) observed the presence of subjects infected by Trypasonoma rhodesiense, without any ill effect. In 1963, with Limbos, we isolated a feebly virulent Trypasonoma gambiense in a healthy subject coming from Zaire. ne should not forget the exceptional case stated by Lapeyssonie, of a woman who, 21 years after a laboratory tested infection, was still in perfect health. In a recent case originally from Matadi, (Zaire) we have found a very high level of Rickettsial antibodies at the same time as Trypasonoma.
This induced us to examine a series of sera coming from subjects infected, some by T. rhodesiense , others by T. gambiense. These cases had been parasitologically tested.
Ten sera of T. rhodesiense came from Zambia while ten sera of T. gambiense came from patients in the Ivory Coast. These twenty sera all had active anti-rickettsial antibodies, especially for Rickettsia mooseri. Moreover, four Rhodesiense sera reacted to Coxiella burneti while two sera of the T. gambiense group reacted to Chlamydiae.
We have tried to find out what is the reaction of patients suffering from Chagas sickness. Everyone knows the importance of this parasite in South America. On eight sera of the patients infected by Trypasonoma Cruzi, six had anti Rickettsia mooseri, while three had active antibodies to C. burnetti. These facts should make clear the great importance of parasital and bacterial association, where often nervous symptoms are also to be found.
Bearing in the mind the most worldly wide distributed disease, paludism, we are convinced that Plasmodium is not the only reason of high death rate so often caused by cerebral parasitism.
In 1949, together with Paul Giroud, we followed up several cases near Astrida (Butare, Rwanda). Plasmodium Falciparum was found abundantly in all cases, but inoculation of dying people, has allowed us to isolate several strains of Rickettsia Burnetti. In the years following, together with Paul Giroud, we established the role of Chlamydia or neo-rickettsia, during several epidemics occurring in Kivu, of meningo-encaphilitis, encapho-myocarditis where protozoa were observed together with neo-rickettsia (Jadin and Giroud, 1957).
We also want to mention that toxoplasma living inside cerebral cysts, may act differently following a Rickettsial infection. We have thus observed several patients having epileptical fits, rapidly getting cured by antibiotical treatment.
Since forty years that we systematically look for anti rickettsial antibodies in Europe and Africa, we have made evident, the great importance of those etiologic agents in nervous diseases.
We have made actually more than 200 000 examinations, which  confirm our convictions. Rickettsia and their transmitters are to be found the world over. Though they are less frequent in Western Europe, they are quite as important and yet totally ignored by many epidiomologists.
During epidemics in Russia, as well as in Poland, research has been made  which made it possible to isolate the infecting agents from sick people as well as from those presenting no symptoms whatever. Still, the emigrated people, though not sick themselves but having lived among  sick people are responsible for introducing the typhus in the USA. This form of disappearing and reappearing disease is commonly known as Brills Disease.
As early as 1911, Charles Nicolle noted the extreme importance of unapparent diseases, firstly noted in guinea pigs, and later on, in man (Nicolle, 1925). 
Rickettsia are, without doubt, the cause of many nervous troubles. Multiple Sclerosis is among those we have done most research on. Following Paul Giroud and Paul Le Gac, we have shown the presence of anti-rickettsial antibodies in quite a number of patients suffering from M.S. In some cases, we could find which Rickettsia was the cause. (Jadin, 1962).
P. Le Gac and associates’ treatment with large spectrum antibiotics, proves to be a decisive argument. Hundreds of patients can walk, see and live  once more a normal life ( Legag,1986) .
These last months, together with fellow workers, we have shown that many other diseases such as epilepsy, Parkinsons Disease, caracterial children are nearly always due to Rickettsia. (Le Gac 1986; Bottero, 1986).

Keeping in mind a, Henri Baruk comes to the conclusion that they lead to a turning point in neurology and thus to its treatment of a patient if is not in too poor a condition.

We use the pulse antibiotherapy  (bacteriostatic + bactericidal), probiotics, antifungal, PPI and vitamins B complex on various conditions since 1992 in South Africa and worldwide.
The reason we carry on the same way is our success rate.

Last Updated (Sunday, 05 September 2010 17:40)

Copyright © 2009 Dr Cecile Jadin.
All Rights Reserved.

About Sugar

In the evolution of humankind, diet refined sugar is probably the last introduced source of calories.
It comes mainly from sugar cane grown in tropical and sub-tropical countries which reached Europe from the East as early as AD 636 and from beetroot where extraction developed in the early 1800’s, in temperated areas.
Refined sugar was then a luxury item sold in pharmacies. It was consumed in moderation; less than 1kg per year. Today an average person will consume about 40kg per annum. Sugar has become a giant in the global food market aided by advertising and a new culture. Why?
Sweetness and taste buds are not the only elements responsible for this addiction. Our parents have used sugar in the education process as a persuasive tool and a reward, even calling their loved ones sweetie or honey. In French sweeties are called bonbon which means ‘goodgood’.
This phenomenon is recent. For today’s elderly population, Coca-Cola is associated with a birthday party or a sea holiday resort – rare occasions.
Today, a normal shopping trolley will contain a few bottles of cold drink, ice cream, sugar, chocolate, cakes and other sweets, processed food. 80% of which is filled with sugar as an ingredient.
When sugar and carbohydrates are digested, specific enzymes split them a nd the result yields two molecules, glucose and fructose.
Glucose is essential for life. It runs in our blood at a constant level which is strictly maintained by hormones. Glucose is the source of energy for our cells and even with no refined sugar intake, it will be metabolised from glycogene, an unlimited source of sugar embedded in our muscles and our liver.
This is why sugar is so bad for our health. Our cells will use it instead of Glycogene and fat will accumulate causing obesity, cancer, cardio-vascular disease, dental cavities, diabetes and mental disorders. For people suffering from chronic infections, this source of energy boosts the germ division and secondarily weakens the immune response.

Any food package containing refined sugar should have a warning label like a cigarette box. What about Coca-Cole, Fanta etc and other multi-national suppliers?
There is certainly something else to do with sugar cane and sugarbeet. Brazil knows it. Over the last 30 years they have managed to produce 80% of their fuel needs based on ethanol sugar cane, from their plantations.
In the future, we might fill our vehicles with Coke at the bio-fuel station, leaving less sugar on the shelves.

About cholesterol

Cholesterol is often described as having a similar effect as that of a chalky deposit in plumbing pipes: if too high, it will produce a blockage of the arteries and give you an heart attack. This seems strange as cholesterol will circulate equally in your whole body. Why is it considered so dangerous by the cardiologist mainly? Is cholesterol their stronghold? Why would cholesterol not first attack, for example, your eyes or your ear drums where the arteries are narrower?
Why is it given so much value by the insurance policies that do not give a damn about rickettsial and neo rickettsial infections? And what if those agents were the silent killers needing cholesterol to survive?
In fact, many recent studies have shown the lack of link between cholesterol and heart attacks (Doctor Malcom Kendrick – British Medical Association). According to the Framingham Heart Study, 75 % of patients suffering from heart attacks present with a normal level of cholesterol.
Never mind good or bad cholesterol, the use of statines will lower its level by blocking its production. Considering that cholesterol exposed to the sun is in fact a precursor of vitamin D,the statines will lower the level of vitamin D.
Then, if your cholesterol is elevated, both statines and, after a while, vitamin D should be prescribed for the rest of your life. What a blessing for the pharmaceutical industry! What an act of robbery under the facade of Medicine!
Statines have a long list of side effects such as severe weakness and muscles pain. This includes our biggest muscle, the heart. In our practice, we have seen more than one spontaneous rupture of tendons. It causes liver toxicity and impairs the memory.
Indeed, the brain is the most cholesterol-rich of all our organs. Children with autism are often lacking of cholesterol and treated with cholesterol supplements.
What a confusing investment!

Diagnosis of Co- infections in chronic medical infectious

The diagnosis of chronic  co-infections opens 4 windows: 

1. The patient’s history: exposure, contacts, travels, traumas …

2. The patient’s symptoms: fatigue is almost always present

3. The patient’s physical examination:
Three signs to be investigated:
– Throat inflammation
– Heart sound (from irregularities to murmurs, clicks etc…) 
– the  Jadin sign i.e. pain or sensitivity of the right iliac fossa (referring to an article of Prof. JB Jadin about Epidemic of appendicitis in a school with lice).

4. The patient’s blood test:
Serology will inform us about the presence of antibodies related to different infections in the blood of a patient. As we all are germ carriers, we need to validate the activities of the antibodies by the presence of dysfunctions. If the dysfunctions looked for are not found, the parasite could be dormant and treatment should not be prescribed.  
The blood test can be compared to a photo – one second vision- as opposed to a video – over a period of time. It can only reveal what is passing in the blood taken by a syringe at this specific time given, only screening ±20 cc of blood out of 5 liters.
One germ is normally not enough to impair the immune system. Furthermore, those germs are symbiotic, completing each other at the enzymatic level to create dysfunction within the patient!

4.1. Infections:
The Rickettsial investigation has to be completed by the following blood tests:
Rickettsial Infection ( Prowazeki, Mooseri, Conori and Coxiella Burnetti )
Chlamydiae pneumoniae and trachomatis
Mycoplasma pneumoniae
Borreliosis or Lyme disease
Helicobacter Pylori

4.2. Dysfunctions:
FBC  and ESR (anaemia, white cell count ↑ or ↓ and the same concerning platelets)
LFT (the liver toxicity of the above germs is common)
Protein electrophoresis (giving us a reading of the immune system condition functioning too low, too high or normal)
Thyroid functions ( T3 and T4 )
Thyroid antibodies (Hashimoto frequency as a start of this condition)
Auto immune factors such as CRP, RF, ANF, CK, Cardiolipines
Iron studies ( elevated ferritin and decreased % of saturation )
Cholesterol – often part of an inflammatory scenery 
Glucose – as a routine exercise
IgE activated by the germs activities as foreign bodies in the human body

Treatment of chronic co-infections in adults according to weight

Pulse Antibiotherapy:
1. Doxycycline 100mg + 50mg daily or 100mg bd plus quinolone : Ciprobay 250 mg or 500 mg bd 
2. Tetralysal (lymecycline) – 300 mg bd x 7 days plus Flagyl ( metronidazole ! no alcohol ) 200 mg bd or 400mg bd
3. Minomycin or cyclomycin 50mg plus 100mg bd or 100 bd plus Rulide (macrolide 150mg.)
4. Vibramycin – only if available as such – 200 to 400 mg/day  in divided doses depending on weight and tolerance
5. Tetralysal is also combined with augmentin 1000mg bd
6. Oxytetracycline + nystatine  250 QID, 500 TDS, 500 QID
7. Doxycycline + Avelon 400 mg or Tavanic BD
8. Klacid XL + Augmentin 1000 mg BD
9. Dalacin C 150 mg 2 x 2 or 2 x 3
10. Tetralysal 300mg BD + Dapsone 50 or 100 mg bd

Each treatment to be taken for 7 to 12 days with:
– Probiotic (not based on milk products) 
– B Complex
– Proton pump inhibitor

In between antibiotherapy:
– In case of the presence of auto immune factors, the use of quinine is often beneficiary keeping in mind the possible side effects, mainly affecting vision
– Thyroid supplements are prescribed when thyroid biological dysfunction  has been detected
– If liver impairment is diagnosed, liver support (legalon) will be used in between   antibiotherapy
– Piracetam (nootropil), increasing the cerebral vascular net, is helpful in case of neurological diseases or memory/concentration impairment
– Peripherical vascular support (betahistine) improves the peripheral circulation
– Beta blockers for tachycardia is sometimes required
– High blood pressure treatment and diabetes treatment as required
– Anti-inflammatories if necessary
– When traveling by air take ecotrin once a day
– De-worm the whole household twice a year
– Co-enzyme Q10 is recommended

At all times during the therapy:
– Avoid caffeine (coffee, coke, red bull etc.) and nicotine because of their vaso-constrictive effects
– Avoid sugar (you will be craving it because infectious pathogens need it to multiply). Do not use aspartame
– Do not consume unpasteurised products – milk, cheese, yoghurt – nor uncooked meat or fish
– Avoid deep body massage as you are dealing with a vascular disease- you will not only recycle ‘cold germs’ but also tear damaged vessels
– Avoid flu vaccines, gamma- or beri- globulin and cortisone
-Do not have local anesthetic containing adrenalin

When patients are asymptomatic and when the blood test concerning the differing dysfunctions and auto-immune factors are normalised, the treatment has achieved its purpose and is discontinued. This might happen after 6 months but most probably will require one to three years or more. Maintenance treatment is advised to patients that have been presenting auto-immune factors.

Oxygen therapy, ionized air and ozone therapy are not a great help because intra-cellular germs are acting like a screen between the blood and the tissue. I have not much experience in hyperbaric therapy as access to it is not easy in South Africa. Le Gag reported in 1986 some success using it for multiple sclerosis. Hyperbaric therapy is known to activate cancer.

During the treatment, sauna or hot baths are important, as well as large intakes of water. The objective being to rid the body of particles of antigens released by the antibiotic. 

Rickettsia may be in a dormant state before the onset of symptoms, and then become activated at the time of onset of symptoms.

Patients with chronic Rickettsia cannot infect others except through the placenta from Mother to Child

Like any other chronic infection (syphilis, Malaria, tuberculosis, leprosy, Aids, herpes, shingles etc.) patients will remain infected.

Sensitivity to sunlight is a side effect of antibiotics. CFS patients also will often be sensitive to any light due to their poor vascularisation.

The sulpha group, like magnesium and sugar, enhance the growth of Rickettsia in guinea pigs, and is to be avoided. 

Vitamin A and E are to be avoided because of their tendency to produce intra-cranial micro-hemorrhages.

To minimise Herxheimer reaction, increase your intake of water.  Probenecid helps as a powerful anti inflammatory. Regular daily exercise for short periods of time will help the circulation of your toxins and hot baths will expel them through the skin.

The immune system’s response to infections

IgM and IgG: The message behind this

The signification of both immune system responses  to various antigens has not stopped intriguing me.
It started a few years ago when I had a patient presenting with all the symptoms of an acute bilharzia but with negatives tests results – urine and blood. I decided to treat him with praziquantel and to repeat the blood test for bilharzia 3 months later. The result came back showing high positivity in IgM
I repeated this treatment very often afterwards and for various pathologies. I frequently observed an increase of IgG and the apparition – not necessarily constant – of the IgM
My (inconclusive?) conclusion is:
– when pathogenic DNA enters the blood vessel, the IgM attempts to neutralise the germ;
– however, these intracellular germs take flight and enter the tissue;
– the IgM, being a bigger molecule, cannot follow the germ into the tissue;
– in response, the IgG, being a smaller molecule, are therefore able to take over the body’s defense within the tissue.
Thus, the IgM can only act as a defense in the circulating system.The presence of both IgM and IgG are both related to the original chronic infection, rather than the common perception that they relate to new and old infections, respectively. To compound the confusion, some patients can only produce one kind of the above-mentioned antibodies (IgM and IgG) regardless of the length of their disease.

Would it be wise to abandon the appellation Lyme in favor of Borreliosis?

Lyme disease

  • Drury discovers Malgache fever in 1702 – Central Africa – following the bite of the ornithodorus moubata tick
  • Early 1900’s Spirochete hispanicum in Spain
  • A few years later, Nicolle tracks Malgache fever – Northern Africa
  • Scheltz, while working in Congo in 1933, reports the same recurrent fever associated with spirochete
  • In 1944, Palakov publishes that the relapsing fever disabling patients in Cape Town is due to the same bug
  • Heisch claims the recognition of Borreliosis as causing the never-ending fever in 1950– Kenya
  • Borrelia burgdoferi, isolated in 1982 by Willy Burgdorfer after a mysterious outbreak of arthritis in Connecticut in 1975, is Americanised as Lyme disease
  • Otzi the Iceman died around 5.300 years ago. His mummified body was found on a high mountain pass in the Otzal Alps in 1991. By means of computer tomography scans, the mummy showed evidence of arteriosclerosis. Traces of DNA from Borrelia burdoferi were also found, according to the Scientific American 2013. 
  • Conclusion: All the above points discredit the thesis that you need a journey in the Connecticut to suffer from  the particular tick born disease called Borreliosis